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Applied Spectroscopy Online

Surface-Enhanced Raman Scattering Based Glucose Sensor

 Presented by Chanda Yonzon of Northwestern University

                                                                                                               According to World Health Organization, 150 million people in the world suffer from diabetes. Diabetic patients require frequent glucose measurements and careful control of glucose levels for the long-term health outlook. Numerous studies have been performed toward developing a real-time, quantitative, and biocompatible glucose sensor.  This work presents a surface-enhanced Raman scattering (SERS) based glucose sensor. Ethylene glycol-terminated alkanethiol is self-assembled on a silver film over nanosphere to partition glucose within the zone of electromagnetic field enhancement.  Glucose concentration is quantitatively predicted using a Chemometric method and presented in the industry standard Clarke error grid.  Moreover, stability, reusability, and biocompatibility of this glucose sensor will be discussed.